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Research PaperMigration of mesenchymal stem cells to tumor xenograft designs and in vitro drug shipping by doxorubicin Senthilkumar Kalimuthu, Liya Zhu, Ji Min Oh, Prakash Gangadaran, Ho Gained Lee, Se hwan Baek, Ramya Lakshmi Rajendran, Arunnehru Gopal, Shin Younger Jeong, Sang-Woo Lee, Jaetae Lee, Byeong-Cheol Ahn Int. J. Med. Sci. 2018 15(ten): 1051-1061. doi: Abstract Entire text PDF

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Prva toplotna črpalka, je nastala v Ameriki, ko je leta 1940 Robert C. Weber popolnoma nenamerno odkril, da je izstopna cev hladilnika za hlajenje sistema tako vroča, da si z njo lahko opečeš roko. Tako je spoznal, da bi se dalo to toploto izkoristiti. Zato je izvedel poskus in svoj grelnik vode povezal s hladilnikom, rezultat katerega je bila večja količina tople vode, kot jo je njegova družina lahko porabila.
 
Z rezultati je bil tako zadovoljen, da se je odločil zgraditi toplotno črpalko, ki bo sposobna ogrevati celoten dom in že naslednje leto je Webber prodal svojo peč na premog.